Download Activation of Hormone and Growth Factor Receptors: Molecular by M. N. Alexis, C. E. Sekeris (auth.), Dr. Michael N. Alexis, PDF

By M. N. Alexis, C. E. Sekeris (auth.), Dr. Michael N. Alexis, Prof. Constantin E. Sekeris (eds.)

This quantity comprises the papers offered within the NATO complicated examine Workshop "Activation of Hormone and progress issue Receptors: Molecular Mechanisms and effects" held in Nafplion, Greece on September 25-30, 1988. the target of NATO ARW is to evaluate the kingdom of-the-art in a given clinical quarter and to formulate options for destiny learn in rising parts of technological know-how through selling foreign medical contacts. within the Nafplion assembly this goal used to be reached by way of a global staff of audio system, senior Greek scientists and graduates all for appropriate study components. The Workshop was once made attainable through the beneficiant aid of the medical Council of NATO. We thank Drs. G. Sinclair and L.V. daCunha, administrators of the NATO ARW's and ASI's (Advanced learn Institutes) respectively, for his or her wholehearted help and suggestion. The foreign Union of Biochemistry offered extra trip promises resulting in elevated overseas participation. in addition, the Secretariat of technology and know-how, the Ministry of tradition and Sciences and the nationwide Hellenic examine beginning contributed financially and by way of assisting group of workers. We clearly thank a lot of these corporations for his or her aid. Our heartful thank you also are prolonged to the Mayor of the Municipality of Nafplion, Mr.

Show description

Read Online or Download Activation of Hormone and Growth Factor Receptors: Molecular Mechanisms and Consequences PDF

Similar nonfiction_8 books

Computational Atomic Physics: Electron and Positron Collisions with Atoms and Ions

"Computational Atomic Physics" offers with computational tools for calculating electron (and positron) scattering from atoms and ions, together with elastic scattering, excitation, and ionization procedures. After an introductory bankruptcy on atomic collision conception, chapters are dedicated to the bound-state wavefunctions.

On the Problem of Plateau / Subharmonic Functions

A convex functionality f might be referred to as sublinear within the following experience; if a linear functionality l is ::=: j on the boundary issues of an period, then l:> j within the inside of that period additionally. If we exchange the phrases period and linear junction via the phrases area and harmonic functionality, we receive an announcement which expresses the attribute estate of subharmonic features of 2 or extra variables.

Opial Inequalities with Applications in Differential and Difference Equations

In 1960 the Polish mathematician Zdzidlaw Opial (1930--1974) released an inequality regarding integrals of a functionality and its spinoff. This quantity deals a scientific and updated account of advancements in Opial-type inequalities. The ebook offers an entire survey of ends up in the sector, beginning with Opial's landmark paper, traversing via its generalizations, extensions and discretizations.

Understanding Insulin Action: Principles and Molecular Mechanisms

Each year among 3 and 4 hundred papers are released concerning insulin motion. This amazing ebook fee prevents any writer from includ­ ing an exhaustive bibliography in any assessment or e-book. might be because of this there isn't any unmarried textual content that makes an attempt to hide the results and the mechanism of motion of insulin.

Extra resources for Activation of Hormone and Growth Factor Receptors: Molecular Mechanisms and Consequences

Sample text

1). , 1987). It appears that. EGF is a rather weak inducer of phospholipase C activity. In A431 cells, which overexpress the EGF receptor, EGF evokes a rather small and variable release of intracellularly stored Ca 2+, while accumulation of IP3(1,4,5) is barely detectable. In contrast, EGF-induced increases in other inositol phosphates such as IP1 and 1P2 are readily detectable. Bradykinin and histamine, on the other hand, are among the most potent activators of phospholipase C, resulting in large Ca 2+ signals and prominent increases in inositol phosphate levels.

The putative splice acceptor site at the upstream side and the splice donor site at the downstream side are shown wi th arrows. Matches to consensus sequences for spl; ce donor and acceptor sites are depicted. Figure 2. The human aFGF nucleotide sequence in the coding region is depi cted along wi th exon/i ntron boundari es and the deduced ami no acid sequence. A comparison with the polypeptides encoded by four other FGF-related genes demonstrates significant amino acid identity among the five gene products and perfect conservation of exon/intron boundaries.

Natl. Acad. Sci. 80: 945-949. R (1985) Nature 318: 183-186. R (1985) J. Bioi. Chem. 260: 9470-9478. P. (1984) J. BioI. Chem. 259: 5277-5286. , Roth, J. (1983) Biochem. Biophys. Res. Commun. 116: 1129-1135. H. Moo1enaar The Netherlands Cancer Institute P1esman1aan 121 1066 ex Amsterdam The Netherlands Introduction The proliferation of cells in vivo and in culture is tightly regulated by polypeptide growth factors. Like all polypeptide hormones, growth factors initiate their action by binding to specific, high affinity receptor molecules on the cell surface.

Download PDF sample

Rated 4.21 of 5 – based on 4 votes